450Multidrug Resistant Gram Negative Bacteria in a Cohort of Hematopoietic Stem Cell Transplant Recipients
نویسندگان
چکیده
Hematopoietic Stem Cell Transplant Recipients Richard Larue Jr., MD, MS; Cristina Royo, MD; Sehnaz Alp, MD; Na Lu, MA; Shmuel Shoham, MD; Kieren A. Marr, MD, FIDSA; Infectious Diseases, Johns Hopkins University, Baltimore, MD; Infectious Diseases, Hospital Universitari de Bellvitge, Barcelona, Spain; Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; Johns Hopkins Hospital, Baltimore, MD; Medicine and Oncology, Johns Hopkins Hospital, Baltimore, MD
منابع مشابه
Risk factors for mortality in patients with bloodstream infections during the pre-engraftment period after hematopoietic stem cell transplantation
BACKGROUND Bloodstream infections (BSI) remain a frequent complication during the pre-engraftment period after hematopoietic stem cell transplantation (HSCT), resulting in high mortality rates. This study evaluated risk factors for mortality in hematopoietic stem cell transplant recipients with BSI in the pre-engraftment period. METHODS This prospective case control study was performed at the...
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The epidemiology of bacteremia developing during neutropenia has changed in the past decade, with the re-emergence of Gram-negative (GN) bacteria and the development of multidrug resistance (MDR) among GN bacteria. We conducted a case-control study in order to identify factors associated with bacteremia due to multidrug-resistant Gram-negative (MDRGN) isolates in hematopoietic stem cell transpl...
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Bacterial infections are major complications after Hematopoietic Stem Cell Transplant (HSCT). They consist mainly of bloodstream infections (BSI), followed by pneumonia and gastrointestinal infections, including typhlitis and Clostridium difficile infection. Microbiological data come mostly from BSI. Coagulase negative staphylococci and Enterobacteriaceae are the most frequent pathogens causing...
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Objectives: Graft versus host disease (GVHD) is a life threatening reaction in the stem cell transplantation process. Nowadays Cyclosporine is the most commonly utilized agent for GVHD prophylaxis and it has a major role in successful transplantation. Cyclosporine has been applied for many years in this field but it could be stated that currently no general consensus is available for its optima...
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The detection of multi-resistant bacterial pathogens, particularly those to carbapenemases, in leukemic and stem cell transplant patients forces the use of old or non-conventional agents as the only remaining treatment options. These include colistin/polymyxin B, tigecycline, fosfomycin and various anti-gram-positive agents. Data on the use of these agents in leukemic patients are scanty, with ...
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